DOR YESHORIM, BY THE NUMBERS
In the past three months: July – September 2025
- 5,074 individuals were screened for pre-marital genetic testing.
- 13,447 potential couples (26,894 individuals) called the hotline to request a compatibility check.
- 181 compatibility requests resulted in ‘incompatible’, and genetic counseling was offered to those individuals and their families (see chart below).
- 597 specialized tests were administered for families with rare genetic diseases.
- 90 families affected by unidentified genetic diseases have reached out to us for assistance.
The 181 incompatible results saved families from the following genetic diseases:
| Standard Panel | |
| Aicardi-Goutieres Syndrome (AGS) | 1 |
| Canavan Disease | 4 |
| Congenital Heart Diseases (GDF1) | 8 |
| Cystic Fibrosis | 20 |
| Dihydrolipoamide Dehydrogenase Deficiency | 1 |
| Familial Dysautonomia | 15 |
| Fanconi Anemia Type C | 1 |
| Glycogen Storage Disease Type 1A | 3 |
| Hyperinsulinism | 2 |
| Leukodystrophy, Hypomyelinating 13 | 1 |
| Mucolipidosis IV | 2 |
| Nemaline Myopathy Type 2 | 3 |
| Niemann Pick Disease Type A | 4 |
| Smith Lemli Opitz Syndrome | 4 |
| SLC1A4 Deficiency | 1 |
| Spinal Muscular Atrophy | 4 |
| Tay Sachs Disease | 18 |
| Vici Syndrome | 1 |
| Walker Warburg Syndrome | 6 |
| Warsaw Breakage Syndrome | 4 |
| Wilson’s Disease | 10 |
| Hearing Loss Panel | |
| Autosomal Recessive Deafness 1B – Connexin 26 | 30 |
| Hearing Loss MYO15A | 2 |
| Hearing Loss SPATA5L1 | 1 |
| Hearing loss STRC | 6 |
| Usher Syndrome Type 3A | 1 |
| Specialized Testing* | |
| Amegakaryocytic Thrombocytopenia (CAMT) | 2 |
| Bartter Syndrome Type 2 | 1 |
| Cerebellar Ataxia And Developmental Delay | 2 |
| Cerebrotendinous Xanthomatosis | 1 |
| Congenital Diarrheal Neonatal | 1 |
| Dyskeratosis Congenita 5 | 1 |
| Galactosemia | 2 |
| Gaucher Disease | 4 |
| Mitochondrial Complex V (Atp Synthase) Deficiency, Nuclear Type 6 | 1 |
| Retinitis Pigmentosa 59 | 6 |
| Rothmund-Thomson Syndrome | 1 |
| VLCAD Deficiency | 1 |
| Wollfram Syndrome 1 | 5 |
| Total | 181 |
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*These tests are not yet included in the standard testing panel. They were requested by families currently suffering from the aforementioned diseases to assist with shidduchim and prevent the birth of children with these diseases.
Further funding will allow the standard testing panel to include more of these debilitating diseases.
Statistically Speaking:
141 incompatible matches for debilitating diseases = 282 individuals translates into 141 men and 141 women who will Be”h not face the heartache of children born with recessive, debilitating genetic diseases.
40 incompatibles for Hearing Loss = 80 individuals
This translates into 40 men and 40 women being informed that they face the possibility of
children born with hearing loss.
